The Most Commonly Used Medications


Updated at 2025-02-07

Medications are essential for managing a wide range of health conditions, from chronic diseases like diabetes and hypertension to acute issues like pain and infections. Several medications are commonly prescribed due to their effectiveness in treating prevalent conditions. These medications help manage symptoms, control disease progression, and improve quality of life. Below are 10 of the most widely used medications in the U.S., along with brief descriptions of their uses and benefits:

Levothyroxine (Synthroid) (Learn more on DoseMed)

Use: Treats hypothyroidism (underactive thyroid). It replaces or provides more thyroid hormone to restore normal thyroid function.

Atorvastatin (Lipitor) (Learn more on DoseMed)

Use: A statin medication used to lower cholesterol levels and reduce the risk of heart disease and stroke by reducing "bad" LDL cholesterol.

Lisinopril (Zestril, Prinivil) (Learn more on DoseMed)

Use: An ACE inhibitor used to treat high blood pressure (hypertension), heart failure, and chronic kidney disease by relaxing blood vessels.

Metformin (Glucophage) (Learn more on DoseMed)

Use: The first-line medication for type 2 diabetes, it helps control blood sugar levels by improving the body's sensitivity to insulin and decreasing glucose production in the liver.

Amlodipine (Norvasc) (Learn more on DoseMed)

Use: A calcium channel blocker used to treat high blood pressure and angina (chest pain) by relaxing the blood vessels.

Omeprazole (Prilosec) (Learn more on DoseMed)

Use: A proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and other stomach acid-related conditions.

Hydrocodone/Acetaminophen (Vicodin, Norco) (Learn more on DoseMed)

Use: A combination of an opioid (hydrocodone) and a non-opioid pain reliever (acetaminophen) used to manage moderate to severe pain.

Gabapentin (Neurontin) (Learn more on DoseMed)

Use: Primarily used to treat nerve pain (neuropathy), seizures, and restless legs syndrome by affecting the nervous system.

Albuterol (Ventolin, ProAir) (Learn more on DoseMed)

Use: A bronchodilator used to treat asthma and chronic obstructive pulmonary disease (COPD) by opening the airways for easier breathing.

Prednisone (Learn more on DoseMed)

Use: A corticosteroid used to reduce inflammation and treat various conditions such as allergies, arthritis, and autoimmune diseases.